Status:
NOT_YET_RECRUITING
Cycling-Based Aerobic Exercise Intervention for Individuals With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Lead Sponsor:
University of Alberta
Collaborating Sponsors:
Cross Cancer Institute
Conditions:
Cancer
Adults
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
CYCLE-CIPN is a proof-of-concept study designed to evaluate whether a prescribed aerobic exercise intervention has the potential to reduce the symptoms and functional impact of CIPN. The small number ...
Detailed Description
CIPN is a common and dose-limiting side effect of neurotoxic chemotherapeutic agents used in cancer treatments, with symptoms affecting up to 100% of patients depending on the drug class. These sympto...
Eligibility Criteria
Inclusion
- 18 years or older
- Cancer diagnosis stage I to III
- CIPN: grade 1 (mild)
- Receiving or have received chemotherapy treatment for cancer
- Speak, read and understand English
Exclusion
- Medical conditions that cause additional neuropathy symptoms (i.e. diabetes)
- Any uncontrolled medical conditions
- Will undergo surgery or radiation therapy during the study period
- Are already receiving an aerobic exercise training program
- Are already participating in an exercise-based research study
- Are unable to provide signed informed consent
Key Trial Info
Start Date :
January 15 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2027
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07150117
Start Date
January 15 2026
End Date
June 30 2027
Last Update
November 18 2025
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