Status:
RECRUITING
Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry During Awake Carotid Endarterectomy
Lead Sponsor:
Izmir Katip Celebi University
Conditions:
Carotid Artery Stenosis Symptomatic
Carotid Endarterectomy (CEA) Surgical Patients
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to better understand how well the brain is perfused (supplied with blood and oxygen) during a specific type of surgery called carotid endarterectomy (CEA), which is performed to preven...
Detailed Description
Carotid artery stenosis accounts for approximately 15-30% of ischemic strokes, highlighting the importance of carotid endarterectomy (CEA) as a preventive surgical strategy. One of the most critical i...
Eligibility Criteria
Inclusion
- Adults aged 18 years or older
- Scheduled for elective carotid endarterectomy (CEA)
- Able to tolerate surgery under regional anesthesia (superficial cervical plexus block)
- Availability of bilateral regional cerebral oxygen saturation (rSO₂) measurements by near-infrared spectroscopy (NIRS)
- Successful intraoperative carotid stump pressure (SP) measurement after cross-clamping
- Provided written informed consent
Exclusion
- Incomplete NIRS or SP recordings
- Conversion from regional to general anesthesia
- Intraoperative technical complications preventing monitoring
- History of prior ipsilateral carotid endarterectomy or carotid artery stenting
- Recent major stroke with permanent neurological deficit
- Recent myocardial infarction within the past 3 months
- History of traumatic brain injury within the past 6 months
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07150260
Start Date
September 1 2025
End Date
October 1 2026
Last Update
January 7 2026
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Izmir Katip Celebi University Atatürk Training and Research Hospital
Izmir, Turkey (Türkiye)