Status:
NOT_YET_RECRUITING
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
Lead Sponsor:
Walter Reed National Military Medical Center
Conditions:
Knee Osteoarthritis
Musculoskeletal Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limit...
Detailed Description
Total knee replacement surgery (also called total knee arthroplasty, or TKA) is a common procedure for people with severe knee arthritis or injury. While the surgery often leads to significant pain re...
Eligibility Criteria
Inclusion
- Patients within the MHS who are DEERS eligible undergoing primary TKA at Walter Reed National Military Medical Center (WRNMMC), Surgery Center of Chevy Chase or District Surgery Center
- Age 18 or older
- successful surgical intervention
Exclusion
- Unicompartmental knee arthroplasty (UKA)
- Revision total knee arthroplasty (rTKA)
- Females who are pregnant or nursing
- Allergic to ingredients in PAI or previous adverse reaction to steroids being used in this study
- Diabetics will be excluded from Group 2 (standard PAI + methylprednisolone)
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT07151417
Start Date
September 1 2025
End Date
August 31 2026
Last Update
September 3 2025
Active Locations (1)
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1
Walter Reed National Military Medical Center
Bethesda, Maryland, United States, 20889