Status:
ACTIVE_NOT_RECRUITING
G8, CARG, Frailty, and Nutritional Markers in Predicting Chemotoxicity
Lead Sponsor:
Çanakkale Onsekiz Mart University
Conditions:
Geriatric Oncology
Oncology
Eligibility:
All Genders
65+ years
Brief Summary
This study aims to evaluate the ability of G8, CARG, and Frailty scales to predict chemotherapy-related toxicity and the need for G-CSF in elderly cancer patients. It also investigates their correlati...
Detailed Description
Background: Aging is associated with decreased physiological reserves, making elderly cancer patients more vulnerable to chemotherapy toxicity (CT). Traditional performance scales like ECOG may be ins...
Eligibility Criteria
Inclusion
- Age ≥ 65 years
- Diagnosed with solid tumor malignancy
- Planned to undergo at least two cycles of adjuvant, neoadjuvant, or metastatic chemotherapy
- Clinically stable condition
- Provided written informed consent
Exclusion
- Presence of hematological malignancies
- Concurrent hormonal therapy, targeted therapy, immunotherapy, or radiotherapy
- Acute infection or advanced organ failure (cardiac, hepatic, renal)
- Cognitive or psychiatric impairment preventing test participation
- Prior treatment with G-CSF
Key Trial Info
Start Date :
January 2 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07151794
Start Date
January 2 2025
End Date
April 1 2026
Last Update
September 3 2025
Active Locations (1)
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1
Çanakkale Onsekiz Mart Univercity
Çanakkale, Turkey (Türkiye), 17020