Status:
ACTIVE_NOT_RECRUITING
Serum IGF-1 and IGF-1Ec in Malignancy Assessment
Lead Sponsor:
Çanakkale Onsekiz Mart University
Conditions:
Cancer
Solid Tumor Malignancies
Eligibility:
All Genders
18+ years
Brief Summary
This cross-sectional study investigates the relationship between serum IGF-1 and IGF-1Ec (E-peptide/MGF) levels and tumor burden in patients with solid tumors. By analyzing serum samples using ELISA a...
Detailed Description
Background: Insulin-like Growth Factor-1 (IGF-1) and its splice variant IGF-1Ec (also known as Mechano Growth Factor, MGF) play critical roles in cell proliferation, survival, and tumor progression. R...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Histologically confirmed diagnosis of a solid tumor
- Clinically stable condition, prior to chemotherapy or during standard follow-up
- Ability to provide informed consent
Exclusion
- Hematological malignancies (e.g., leukemia, lymphoma)
- Acute or chronic liver or kidney failure
- Current use (within 1 month) of corticosteroids, growth hormone, or medications affecting IGF-1 levels
- Pregnancy or lactation
- Coagulopathy or severe anemia preventing safe venipuncture
Key Trial Info
Start Date :
April 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07151807
Start Date
April 1 2025
End Date
December 1 2026
Last Update
September 3 2025
Active Locations (1)
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1
Çanakkale Onsekiz Mart University
Çanakkale, Turkey (Türkiye), 17020