Status:
RECRUITING
Triglycerides Glucose Index on Angiographic Profiling of Non-Diabetic Premature Coronary Artery Disease Patients
Lead Sponsor:
Sohag University
Conditions:
Triglycerides Glucose Index
Angiographic Profiling
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to evaluate the impact of the triglyceride-glucose (TyG) index on the angiographic profiling of non-diabetic patients with premature coronary artery disease (CAD).
Detailed Description
Premature coronary artery disease (CAD), defined as CAD occurring before the age of 55 in men and 65 in women, has emerged as a growing health concern worldwide. Insulin resistance and associated met...
Eligibility Criteria
Inclusion
- Age ≥18 years old.
- Both sexes.
- Non-diabetic patients \[no history of diabetes, hemoglobin A1C (HbA1C) \< 6.5%, fasting glucose \< 126 mg/dL\].
- Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography.
Exclusion
- Known diabetes mellitus (type 1 or type 2).
- Previous history of coronary revascularization.
- Severe hepatic or renal dysfunction \[alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)\< 30 mL/min/1.73 m²\].
- Malignant disease, autoimmune disease, or systemic inflammatory disorders.
- Current use of triglyceride-lowering medications.
Key Trial Info
Start Date :
September 4 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT07154186
Start Date
September 4 2025
End Date
February 1 2026
Last Update
September 5 2025
Active Locations (1)
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1
Sohag University
Sohag, Egypt, 82511