Status:
RECRUITING
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
Lead Sponsor:
The University of Texas Health Science Center at San Antonio
Conditions:
Tooth Extraction
Eligibility:
All Genders
18-89 years
Phase:
NA
Brief Summary
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink". The bone graft ...
Detailed Description
At the end of this study the researchers hope to learn the following: How much new bone formation occurs inside the tooth socket at approximately 16 weeks of healing after ridge preservation with calc...
Eligibility Criteria
Inclusion
- Male or female patient aged 18 to 89
- One tooth, excluding molars, that has been identified by dental faculty as requiring a single tooth extraction
- A dental implant is indicated and treatment planned to replace the missing tooth
- Site has adequate restorative space for a dental implant-retained restoration
- Site has at least 10mm of alveolar bone height, without impinging on the maxillary sinus or inferior alveolar canal.
- Site has a dehiscence of the buccal or lingual bony plate of the tooth socket extending no more than 50% of the total depth of the socket.
- Female patients who have undergone a hysterectomy, tubal ligation, or menopause, and nonpregnant women of child-bearing potential.
- Patients are nonsmokers or former smokers. Current smokers may be included if they smoke \<10 cigarettes per day (less than or equal to 10 cigarettes per day)
Exclusion
- Patient allergic to bovine-derived collagen products, Bacitracin, Gentamicin, Polymyxin
- Patients who will not cooperate with the follow-up schedule.
- Patients will not be entered who are mentally incompetent, prisoners, or pregnant.
- Pregnant women or women intending to become pregnant during the study period (as confirmed verbally; an over-the-counter pregnancy test will be provided if pregnancy status is unknown or suspected).
- Patients who become pregnant during the study will be withdrawn and standard care will be delivered.
- Smokers who smoke \>10 cigarettes per day (more than 10 cigarettes per day)
Key Trial Info
Start Date :
November 19 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT07154693
Start Date
November 19 2025
End Date
December 31 2027
Last Update
January 6 2026
Active Locations (1)
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1
University of Texas Health Science Center at San Antonio School of Dentistry
San Antonio, Texas, United States, 78229