Status:

NOT_YET_RECRUITING

Serum Surfactant Protein-D as Predictor of Disease Severity in Hospitalized COPD Patients

Lead Sponsor:

Assiut University

Conditions:

COPD

Eligibility:

All Genders

40-88 years

Brief Summary

evaluation of the serum levels of surfactant protein-D (SP-D), C-reactive protein (CRP), fibrinogen, and peripheral blood neutrophilic and eosinophilic counts in patients with COPD correlation of thes...

Detailed Description

Chronic Obstructive Pulmonary Disease (COPD) is a chronic progressive inflammatory disease of the airways and lungs, mainly caused by cigarette smoking and environmental exposures .It is characterized...

Eligibility Criteria

Inclusion

  • Adults ≥40 years diagnosed with COPD based on prior diagnosis or spirometry if available.
  • Admission for acute exacerbation (AECOPD) in ward or Respiratory ICU.

Exclusion

  • Active pulmonary infection unrelated to COPD (e.g. tuberculosis, fungal infections)
  • Other chronic lung diseases such as asthma, interstitial lung disease, or lung cancer
  • Use of systemic corticosteroids for conditions other than COPD exacerbation

Key Trial Info

Start Date :

December 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2027

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT07154953

Start Date

December 1 2025

End Date

January 1 2027

Last Update

September 10 2025

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