Status:

COMPLETED

Assessing Vulnerability and Outcomes of Intracranial Atherosclerotic Plaques

Lead Sponsor:

Xuanwu Hospital, Beijing

Collaborating Sponsors:

The People's Hospital of Liaoning Province

The First Hospital of Jilin University

Conditions:

Asymptomatic Intracranial Atherosclerotic Stenosis Patients

Eligibility:

All Genders

30-80 years

Brief Summary

This prospective cohort study aims to establish a large-scale cohort for primary stroke prevention in asymptomatic intracranial atherosclerosis (ICAS). Objectives include: characterizing risk factor a...

Eligibility Criteria

Inclusion

  • Intracranial arterial stenosis confirmed by transcranial Doppler (TCD), clinically suspected to be of atherosclerotic origin
  • No history of stroke or transient ischemic attack (TIA)
  • Adequate temporal bone acoustic window penetrability

Exclusion

  • Clinically diagnosed non-atherosclerotic etiology-related intracranial arterial stenosis
  • Poor temporal bone acoustic window penetrability
  • Loss to follow-up

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 30 2025

Estimated Enrollment :

3849 Patients enrolled

Trial Details

Trial ID

NCT07156344

Start Date

January 1 2019

End Date

April 30 2025

Last Update

September 5 2025

Active Locations (1)

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Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100053