Status:
NOT_YET_RECRUITING
Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis
Lead Sponsor:
Lanyue Zhu
Conditions:
Postoperative Acute Kidney Injury
Intraoperative Hypotension
Eligibility:
All Genders
18+ years
Brief Summary
Postoperative acute kidney injury (AKI) is a serious complication often linked to low blood pressure during surgery. This study aims to better protect patients' kidneys by personalizing how blood pres...
Detailed Description
1. Study Rationale Postoperative Acute Kidney Injury (AKI) is a common and severe complication following non-cardiac surgery, leading to prolonged hospital stays, increased medical costs, and a higher...
Eligibility Criteria
Inclusion
- Patients undergoing non-cardiac surgery
- Access to intraoperatively available invasive/noninvasive blood pressure monitoring data
Exclusion
- Patients for Age \< 18 yr
- Patients without preoperative or postoperative creatinine records
- Patients undergoing urinary surgeries
- Patients with chronic kidney injury before surgery
- ASA grade \> 5 class
- Anesthesia duration \< 60 min
- Patients for non-available lowest blood pressure data during surgery
- Hemodynamic records loss more than 25% of the total anesthesia duration
- Patients for categorical variables records missing
Key Trial Info
Start Date :
September 9 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
44504 Patients enrolled
Trial Details
Trial ID
NCT07156474
Start Date
September 9 2025
End Date
December 31 2026
Last Update
September 5 2025
Active Locations (1)
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1
Zhongda Hospital Southeast University
Nanjing, Jiangsu Provincce, China, 210000