Status:
NOT_YET_RECRUITING
Associating Gastric Infection With Autoimmune Flare Severity in an Egyptians
Lead Sponsor:
Assiut University
Conditions:
H. Pylori
SLE - Systemic Lupus Erythematosus
Eligibility:
All Genders
18+ years
Brief Summary
A cross-sectional, observational study aims to evaluate the relationship between Helicobacter pylori infection and disease activity in patients diagnosed with systemic lupus erythematosus (SLE), using...
Detailed Description
the study explores the potential role of chronic H. pylori infection as a trigger or aggravating factor in SLE, an autoimmune disorder characterized by overactive immune responses that cause multisyst...
Eligibility Criteria
Inclusion
- Adult patients (aged ≥18 years) with a confirmed diagnosis of SLE according to the American College of Rheumatology (ACR) or Systemic Lupus International Collaborating Clinics (SLICC) classification criteria.
- Patients who provide written informed consent to participate in the study. Patients who have not received antibiotics or proton pump inhibitors (PPIs) in the four weeks
Exclusion
- Patients with a history of gastric surgery or known gastrointestinal malignancy.
- Patients currently receiving immunosuppressive therapy for conditions other than SLE.
- Patients with coexisting autoimmune diseases other than SLE.
- Pregnant or lactating women.
- Patients with active infections (other than H. pylori) at the time of enrollment.
Key Trial Info
Start Date :
August 30 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2027
Estimated Enrollment :
115 Patients enrolled
Trial Details
Trial ID
NCT07157202
Start Date
August 30 2026
End Date
December 30 2027
Last Update
September 5 2025
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