Status:

COMPLETED

Exercise Capacity, Muscle Oxygenation, Respiratory Muscle Strength, and Physical Activity Level in Pediatric CF and PCD

Lead Sponsor:

Gazi University

Conditions:

Cystic Fibrosis (CF)

Primary Ciliary Dyskinesia (PCD)

Eligibility:

All Genders

6-18 years

Brief Summary

Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are genetic diseases characterized by chronic respiratory tract infections. In both diseases, impaired mucociliary clearance, recurrent respir...

Detailed Description

In patients with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD), lower extremity exercise capacity, skeletal muscle function, respiratory muscle strength, and physical activity levels are l...

Eligibility Criteria

Inclusion

  • Cystic fibrosis patients;
  • Patients diagnosed with cystic fibrosis according to the American Cystic Fibrosis Association consensus report
  • Between the ages of 6 and 18
  • Clinically stable conditions
  • Primary ciliary dyskinesia patients;
  • Patients diagnosed with primary ciliary dyskinesia according to the American Thoracic Society (ATS) and European Respiratory Society (ERS) guidelines
  • Between the ages of 6 and 18
  • Clinically stable conditions
  • Healthy controls;
  • Agreeing to participate voluntarily in the study
  • Between the ages of 6 and 18

Exclusion

  • Patients;
  • Uncooperative
  • Orthopedic or neurological disorders that will affect functional capacity
  • Pneumonia or any acute infection
  • Healthy controls;
  • Chronic disease
  • Uncooperative
  • Orthopedic or neurological disorders that will affect functional capacity

Key Trial Info

Start Date :

January 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2025

Estimated Enrollment :

88 Patients enrolled

Trial Details

Trial ID

NCT07157644

Start Date

January 1 2021

End Date

March 1 2025

Last Update

September 5 2025

Active Locations (1)

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Gazi University Faculty of Health Sciences Department of Cardiopulmonary Physiotherapy and Rehabilitation

Ankara, Çankaya, Turkey (Türkiye), 06490