Status:
NOT_YET_RECRUITING
Molecular Underpinnings of Heart Failure, Integrative Multi-Omics, and Non-Coding RNA Profiling
Lead Sponsor:
University of Zurich
Conditions:
Heart Failure
Heart Failure (for Example, Fluid Overload)
Eligibility:
All Genders
Brief Summary
The main objective of the study is to achieve a comprehensive phenotyping of patients with heart failure, combining detailed clinical characterization with in-depth molecular profiling. By integrating...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA
- Female and Male, age ≥18 years at screening.
- Diagnosis of Heart Failure according to ESC Heart Failure Guidelines
- Ability to understand the requirements of the study and to provide informed consent.
- Willingness to undergo follow-up.
- EXCLUSION CRITERIA
- Patients will be excluded if they meet any of the following conditions:
- Active malignancy or history of cancer with ongoing treatment (e.g., chemotherapy, radiotherapy, immunotherapy).
- Autoimmune or systemic inflammatory diseases.
- Concomitant infections, including acute systemic infections (e.g., sepsis, pneumonia) or chronic infections with systemic impact (e.g., HIV, hepatitis B/C with elevated transaminases).
- Other exclusion criteria:
- Age\<18 years old
- Inability to provide written informed consent
Exclusion
Key Trial Info
Start Date :
November 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2031
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT07158086
Start Date
November 1 2025
End Date
November 30 2031
Last Update
September 10 2025
Active Locations (1)
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1
University Hospital of Zurich
Zurich, Switzerland, 8091