Status:
NOT_YET_RECRUITING
Combined tDCS and Cognitive Training as an Adjunctive Treatment in Opioid Use Disorder
Lead Sponsor:
University of Minnesota
Conditions:
Opioid Use Disorder
Buprenorphine
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The overall goal of this study is to investigate the added benefit of a neuromodulation intervention in individuals under buprenorphine maintenance treatment for OUD (bOUD).
Eligibility Criteria
Inclusion
- ability to provide consent and comply with study procedures
- Diagnostic and Statistical Manual of Mental Disorders criteria for OUD
- undergoing buprenorphine maintenance treatment. Participants may have current comorbid drug use, but primary diagnosis must be OUD
- Intention to remain in the addiction treatment program until intervention completion.
Exclusion
- Any medical condition with neurological sequelae
- head injury resulting in skull fracture or loss of consciousness of \>30 minutes
- any tDCS or MRI contraindication (tDCS: history of seizures, metallic cranial plates/screws or implanted device, history of eczema on scalp. MRI: unapproved metallic implants, pacemakers or any other implanted electrical device, shrapnel, metallic braces, non-removable body piercings, pregnancy, breathing or movement disorder, or claustrophobia)
- any psychotic disorder (participants with other treated and stable psychiatric disorders will be included)
- presence of a condition that would render study measures impossible to administer or interpret
- age younger than 18
- primary current substance use disorder on a substance other than opioids except for caffeine or nicotine
- court mandated treatment
- pregnancy
- disrespectful behavior towards the investigators and staff.
Key Trial Info
Start Date :
January 15 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT07158853
Start Date
January 15 2026
End Date
August 1 2026
Last Update
November 25 2025
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455