Status:
RECRUITING
Vaginal Estrogen Treatment and Effect on Hemostatic Parameters in Postmenopausal Women
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
University of Southern Denmark
Conditions:
Vagina Atrophy
Eligibility:
FEMALE
50+ years
Phase:
PHASE4
Brief Summary
This study investigates whether vaginal estrogen treatment has an effect on hemostatic parameters in postmenopausal women. Blood samples are collected before and after 3 months treatment to assess cha...
Detailed Description
This prospective cohort study includes 90 postmenopausal women aged ≥ 50, having vaginal atrophy symptoms and indication for treatment with vaginal estrogen tablets 10 µg at least 3 times a week for 3...
Eligibility Criteria
Inclusion
- Postmenopausal women aged ≥ 50
- Symptomatic vaginal atrophy
- Indication for standard treatment with vaginal estrogen tablets 10 µg at least three times a week
- Study population 1: without a history of venous thromboembolic event
- Study population 2: with a history of venous thromboembolic event
Exclusion
- Unable to give written informed consent
- Does not speak Danish
- Current cancer treatment
- Current treatment with blood thinning medication (except plateletinhibitor)
- Current treatment with local or systematic estrogen
- Systemic inflammatory disease, liver disease or kidney disease
Key Trial Info
Start Date :
March 21 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT07160504
Start Date
March 21 2025
End Date
December 31 2026
Last Update
September 8 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark
Aarhus N, Denmark, 8200