Status:
RECRUITING
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
Lead Sponsor:
St. James's Hospital, Ireland
Collaborating Sponsors:
Tallaght University Hospital
Conditions:
Asthma (Diagnosis)
OSA - Obstructive Sleep Apnea
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma...
Detailed Description
Obstructive sleep apnoea (OSA) and asthma are two of the most common respiratory disorders worldwide, with asthma estimated to affect 300 million, and OSA in the region of 1 billion people. As a resul...
Eligibility Criteria
Inclusion
- Patients must have a clinical diagnosis of asthma with supportive objective diagnostics including but not limited to, variable airflow obstruction, bronchial-hyper responsiveness and demonstrable eosinophilic inflammation via fractional exhaled nitric oxide or peripheral eosinophilia
- Patients receiving step 4 or step 5 of 'The Global Initiative for Asthma' (GINA) treatment guidelines will be selected
- Between the ages of 18 to 90 years of age
Exclusion
- Patients with previous sleep study investigations
- Excessive daytime sleepiness; ESS \>17
- Previous diagnosis of a sleep disorder
- Resting hypoxaemia or need for long-term oxygen therapy
- Inability to provide informed consent
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07160868
Start Date
September 1 2025
End Date
April 1 2026
Last Update
September 8 2025
Active Locations (1)
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1
St. James's Hospital
Dublin, Dublin, Ireland