Status:
NOT_YET_RECRUITING
The Influence of Different PEEP Levels After Recruitment Maneuvre on the Effect of Alveolar Recruitment Maintenance and Patients' Cardiac Function
Lead Sponsor:
Northern Jiangsu People's Hospital
Conditions:
Pulmonary Atelectasis
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
During general anesthesia surgery, the role of positive end-expiratory pressure (PEEP) in mechanical ventilation remains uncertain. Pressure levels above 0 cm H₂O can prevent postoperative pulmonary c...
Eligibility Criteria
Inclusion
- ASA physical status classification: Ⅰ or Ⅱ or Ⅲ
- Adults aged 18 to 80 years, regardless of gender.
- Patients undergoing elective laparoscopic surgery under general anesthesia.
- Patients who have provided written informed consent after understanding the study purpose, procedures, and potential risks.
Exclusion
- Recent thoracic surgery; chest X - ray or CT indicating pneumothorax, emphysema, or pulmonary bullae;
- Pulmonary diseases: asthma, severe obstructive ventilatory dysfunction; preoperative pulse oxygen saturation (SpO2) \< 90% in room air or SpO2 \< 95% with oxygen supplementation; contraindications for lung recruitment: high intracranial pressure, hypovolemic shock, right heart failure;
- Severe heart disease (New York Heart Association, NYHA Class III or IV; acute coronary syndrome or sustained ventricular tachyarrhythmia); participation in other interventional studies or refusal to be enrolled.
Key Trial Info
Start Date :
August 30 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 30 2025
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT07161466
Start Date
August 30 2025
End Date
November 30 2025
Last Update
September 8 2025
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