Status:
RECRUITING
Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Approach/Avoidance Behavior
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study will assess the long-lasting effects of personalized theta burst stimulation (TBS), a repetitive form of transcranial magnetic stimulation (TMS), over the left prefrontal cortex on the appr...
Detailed Description
This is a double-blinded, counterbalanced crossover study in healthy adults. Volunteers will participate in four TBS-EEG sessions. In each, the investigators will first conduct the approach/avoidance ...
Eligibility Criteria
Inclusion
- Participants must be legal adults between the ages of 18 to 65;
- Able and willing to complete study procedures and tasks.
Exclusion
- History or evidence of chronic neurological or mental disorder;
- Chronic condition that requires pharmacological treatment over the course of study participation;
- Pregnancy or breastfeeding;
- History or evidence of alcohol or drug addiction;
- Contraindications for transcranial magnetic stimulation (history of seizures, metallic or electric implant in the head/neck area);
- Contraindications for magnetic resonance imaging at 3 Tesla (non-compatible implants, metallic foreign bodies, insulin pump, pacemaker).
Key Trial Info
Start Date :
July 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2026
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT07161505
Start Date
July 31 2025
End Date
August 31 2026
Last Update
September 8 2025
Active Locations (1)
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1
Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States, 60611