Status:
ENROLLING_BY_INVITATION
Effect of Home-Based Transcranial Direct Current Stimulation on Pain in Patients With Rheumatoid Arthritis With Low Inflammatory Activity
Lead Sponsor:
Federal University of Rio Grande do Sul
Conditions:
Rheumatic Arthritis
Chronic Pain
Eligibility:
FEMALE
18-70 years
Phase:
NA
Brief Summary
Rheumatoid arthritis (RA) is a highly complex inflammatory autoimmune disease. Several drugs have been developed in recent decades to target the immune components of inflammation. However, even with e...
Detailed Description
Rheumatoid arthritis (RA) is a highly complex inflammatory autoimmune disease. Several drugs have been developed in recent decades to target the immune components of inflammation. However, even with e...
Eligibility Criteria
Inclusion
- Participants aged 18-70 with RA.
- Participants with generalized pain ≥ 40 mm on the VAS-Pain scale, lasting over 3 months, and not of mechanical or inflammatory origin, as assessed by a certified rheumatologist.
- Evidence of low inflammatory markers, including with C-reactive protein (CRP) \<10 mg/dL and sedimentation rate (ESR) \<20 mm/h, and stable treatment for PsA for at least 6 months prior to study enrollment.
Exclusion
- History of brain surgery, traumatic brain injury, stroke, previous intracranial metal implantation, pregnancy, or breastfeeding.
- Previous history of autoimmune diseases other than RA.
- History of neurological diseases.
- Previous history of neoplasia.
- History of any other uncompensated clinical disease.
- Use of illicit drugs within the past 6 months.
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 22 2028
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT07162311
Start Date
January 1 2024
End Date
December 22 2028
Last Update
September 9 2025
Active Locations (1)
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1
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil, 90880390