Status:
RECRUITING
A Study on the Modulation of Gut Microbiota by Oral Sialic Acid in Healthy Subjects
Lead Sponsor:
Xiaolong Li
Conditions:
Taking Sialic Acid to Regulate the Gut Microbiota
Healthy
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This is a single-center prospective cohort study conducted by the Department of General Surgery at the Second Affiliated Hospital of Army Medical University (Xinqiao Hospital). The purpose of this stu...
Detailed Description
Background：Colorectal cancer (CRC) is one of the most common gastrointestinal malignancies worldwide, ranking third in incidence and second in mortality among all cancers. Surgical resection remains t...
Eligibility Criteria
Inclusion
- Aged between 18 and 75 years
- No history of major diseases, no previous surgical history, and no history of cardiometabolic diseases (such as hypertension, diabetes mellitus, obesity, etc.)
- No use of drugs that may affect gut microbiota or metabolic function (e.g., antibiotics, probiotics, immunosuppressants, etc.);
- Voluntarily participate in the study and sign the informed consent form.
Exclusion
- Comorbidities: Complicated with other severe diseases (e.g., immunodeficiency, chronic liver disease, renal insufficiency, malignant tumors, etc.).
- Recent infections: Registration records indicate a history of severe infections in the recent period (within 3 months) or currently receiving anti-infective treatment.
- Special populations: Pregnant women, lactating women, or women planning to become pregnant.
- Poor compliance: Volunteers who are unable to cooperate with the study protocol or follow-up
Key Trial Info
Start Date :
September 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2027
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT07162662
Start Date
September 10 2025
End Date
August 1 2027
Last Update
December 10 2025
Active Locations (1)
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1
Second Affiliated Hospital of Army Medical University
Chongqing, Chongqing Municipality, China, 400037