Status:
ACTIVE_NOT_RECRUITING
Evaluation of Systemic Inflammatory Index and Biomarkers in Relation to Inferior Alveolar Nerve Block Success and Postoperative Pain
Lead Sponsor:
KEZBAN MELTEM ÇOLAK
Conditions:
Postoperative Pain
Inferior Alveolar Nerve Block Failure
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to investigate the relationship between systemic inflammatory markers and the effectiveness of inferior alveolar nerve block anesthesia in patients undergoing dental treatment. The pri...
Detailed Description
Pulpitis is among the most common causes of orofacial pain. Irreversible pulpitis is characterized by a painful pulpal response to thermal stimuli that does not subside immediately after the removal o...
Eligibility Criteria
Inclusion
- Patients aged between 18 and 65 years.
- Patients with a pain score greater than 54 on the Heft-Parker Visual Analog Scale (VAS).
- Patients classified as ASA I according to the American Society of Anesthesiologists (ASA).
- Teeth with probing depths less than 3 mm, suitable for rubber dam placement and restoration.
- Vital mandibular molar teeth with a clinical diagnosis of irreversible pulpitis, confirmed by pulp vitality tests (electric pulp testing and cold testing).
- Presence of bleeding upon access to the pulp chamber.
- No use of non-steroidal anti-inflammatory drugs (NSAIDs) within the last 12 hours.
- Absence of allergy to articaine.
- Patient's consent to provide a blood sample.
Exclusion
- Patients classified as ASA II or higher.
- Pregnant women or those with suspected pregnancy.
- Patients with periodontal pockets greater than 3 mm in the involved tooth.
- Patients who received treatment with NSAIDs within the last 12 hours.
- Patients allergic to articaine.
- Teeth that had undergone previous endodontic treatment.
- Teeth with extensive structural loss preventing rubber dam isolation.
- Presence of internal or external root resorption.
Key Trial Info
Start Date :
September 27 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 15 2025
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT07163065
Start Date
September 27 2024
End Date
October 15 2025
Last Update
September 9 2025
Active Locations (1)
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1
Atatürk University Faculty of Dentistry, Department of Endodontics
Erzurum, Erzurum, Turkey (Türkiye), 25240