Status:
NOT_YET_RECRUITING
Analysis of the Influence of Dialysis Fluid Composition on Vascular Calcification in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Lead Sponsor:
Hospital Clinic of Barcelona
Conditions:
Vascular Calcification
Hemodialysis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to find out if using a citrate-based dialysate with added magnesium during hemodialysis can help slow down or prevent the hardening of blood vessels (vascular calcif...
Detailed Description
Vascular calcification is a common and serious complication in patients receiving long-term hemodialysis. Dialysate composition may influence its progression. Acetate, a weak acid, has traditionally b...
Eligibility Criteria
Inclusion
- Adults (≥18 years old) on maintenance hemodialysis for more than 3 months
- Clinically stable patients with a well-functioning vascular access
- Residual urine output ≤ 250 mL/day
- Able and willing to provide written informed consent
Exclusion
- Known allergy or intolerance to any component of the dialysates
- Active malignancy or infectious/inflammatory disease
- Planned living donor kidney transplant before study completion
- Current treatment with vitamin K antagonists (coumarins)
- Severe hypocalcemia or poorly controlled secondary hyperparathyroidism
- Any condition that, in the investigator's judgment, contraindicates participation or affects study compliance
Key Trial Info
Start Date :
September 3 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 6 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT07163936
Start Date
September 3 2025
End Date
September 6 2026
Last Update
September 9 2025
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