Status:
COMPLETED
CCS-AMI Staging Diagnosis by High-sensitivity Cardiac Troponin-I
Lead Sponsor:
Indiana University
Collaborating Sponsors:
Indiana University School of Medicine
Synergy Cardiovascular Research Center
Conditions:
Acute Myocardial Infarction (AMI)
Eligibility:
All Genders
18-79 years
Brief Summary
MIRON-CCS is a multicenter retrospective diagnostic study designed to evaluate the role of high-sensitivity cardiac troponin I (hs-cTnI) in the diagnosis and clinical stage classification of acute myo...
Eligibility Criteria
Inclusion
- Age 18-79 years
- Index STEMI
- Coronary angiogram with PCI to occur irrespective of the onset of the symptoms.
- Ability to provide informed consent for themselves
Exclusion
- History of prior myocardial infarction,
- Cardiogenic shock,
- Patients who present with current cardiac arrest
- Any contraindication to cardiac CMR (claustrophobia, pacemaker or cardiac defibrillator, known allergy to gadolinium),
- Presence of permanent atrial fibrillation,
- Unconscious patient,
- Severe renal insufficiency (creatinine clearance ≤ 30 ml/min/m2 or renal replacement therapy),
- Women who are pregnant or breastfeeding. Women of reproductive potential must have a negative pregnancy test.
Key Trial Info
Start Date :
January 10 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2025
Estimated Enrollment :
312 Patients enrolled
Trial Details
Trial ID
NCT07163988
Start Date
January 10 2023
End Date
September 30 2025
Last Update
November 28 2025
Active Locations (2)
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1
Medical Imaging Research Institute
Indianapolis, Indiana, United States, 46202
2
Synergy Cardiovascular Research Center
Rajkot, Gujarat, India