Status:

NOT_YET_RECRUITING

Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients

Lead Sponsor:

Assiut University

Conditions:

Pressor Response

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

Dexmedetomidine nebulization in sever preeclamptic patients

Detailed Description

Dexmedetomidine nebulization for attenuation of pressor response to laryngoscopy and endotracheal intubation in sever preeclamptic patients undergoing caesarean section under general anaesthesia. A pr...

Eligibility Criteria

Inclusion

  • Patients with severe pre-eclampsia scheduled for cesarean section under general anesthesia
  • ASA II, III

Exclusion

  • sever obesity (BMI ≥ 40)
  • Cardiac patients
  • History of diabetes mellitus
  • Renal dysfunction (elevated serum creatinine \> 2mg\\dl)
  • hepatic dysfunction (elevated hepatic enzyme three times above normal)
  • History to hypersensitivity to the tested drug.
  • Emergency surgery
  • Known fetal anomalies

Key Trial Info

Start Date :

October 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 15 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07164326

Start Date

October 15 2025

End Date

December 15 2026

Last Update

September 10 2025

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Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients | DecenTrialz