Status:
ENROLLING_BY_INVITATION
Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial
Lead Sponsor:
Benha University
Conditions:
Ventilator Acquired Pneumonia
Catheter Related Bloodstream Infection
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary goal of this study is to assess the benefit of probiotics in preventing or minimizing of various type of systemic infection in critically ill adult patients.
Detailed Description
Healthcare-associated infections constitute a major focus of public health because of their consequences in terms of mortality, morbidity, and financial costs. Owing to multiple pathophysiological fac...
Eligibility Criteria
Inclusion
- Patients of both genders aged 18 years or older
- Critically ill patients (medical and surgical) with Acute Physiology and Chronic Health Evaluation II \>=10
Exclusion
- Patients with active cancer/on chemotherapy and/or radiotherapy/autoimmune diseases/ immunomodulating drugs/ neutropenic fever.
- Pregnancy
- Relatives refuse to share in the study
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 2 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07164781
Start Date
April 1 2025
End Date
December 2 2025
Last Update
September 10 2025
Active Locations (1)
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1
Benha University Hospitals
Banhā, Qalyubia Governorate, Egypt, 13518