Status:

NOT_YET_RECRUITING

Efficacy of Methylene Blue Plus Ropivacaine for Post-Hemorrhoidectomy Pain.

Lead Sponsor:

The Affiliated Hospital of Putian University

Conditions:

Mixed Hemorrhoids

Milligan-Morgan Hemorrhoidectomy

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

Revised Translation (Academic English): As one of the most prevalent anorectal disorders, mixed hemorrhoids continue to rely on the Milligan-Morgan hemorrhoidectomy as the gold-standard surgical appr...

Eligibility Criteria

Inclusion

  • Aged between 18 and 75 years.
  • Diagnosed with Grade III-IV hemorrhoids according to the Goligher classification.
  • Scheduled to undergo standard Milligan-Morgan hemorrhoidectomy.
  • Procedure performed under spinal anesthesia alone.

Exclusion

  • Pregnancy or lactation.
  • Current immunotherapy or coagulopathies.
  • Contraindications to any protocol-specified agents (e.g., history of severe allergic reactions to methylene blue or ropivacaine).
  • Concurrent anorectal pathologies (e.g., perianal abscess, anal fistula, fecal incontinence).
  • Comorbid systemic conditions (e.g., cardiac/hepatic/renal insufficiency, diabetes mellitus, coagulopathy, peptic ulcer disease).
  • Incomplete perioperative documentation.
  • Inability to comply with follow-up protocols.

Key Trial Info

Start Date :

August 30 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

177 Patients enrolled

Trial Details

Trial ID

NCT07164807

Start Date

August 30 2025

End Date

December 1 2026

Last Update

September 10 2025

Active Locations (1)

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1

Affiliated Hospital of Putian University

Putian, China