Status:
RECRUITING
Timing and Outcomes of Recovery After intraCerebral Hemorrhage
Lead Sponsor:
Xuanwu Hospital, Beijing
Conditions:
Intracerebral Haemorrhage
Intracerebral Hemorrhage
Eligibility:
All Genders
18-80 years
Brief Summary
The TORCH registry is a prospective, observational cohort study, which will collect detailed, longitudinal data on the clinical characteristics, treatment modalities, and outcomes of patients with ICH...
Eligibility Criteria
Inclusion
- Subject Age is ≥18 to ≤80 years
- Subject with a Head CT/CTA that demonstrates an acute, spontaneous, primary, supratentorial ICH, assessed via standard of care techniques
- Subject recieving a surgery intervention
- Subject has a NIHSS score ≥ 6 or GCS score 5≤GCS≤15
- Subject has a baseline Modified Rankin Scale (mRS) Score ≤ 1
Exclusion
- Secondary intracerebral hemorrhage (with leading cause, e.g., Moyamoya disease, arteriovenous malformation, intracranial aneurysm, tumor, brain trauma)
- Pre-stroke life expectancy \< 1 year for severe comorbidities (e.g., Progressive malignant tumor, severe chronic heart failure \[NYHA: III-IV\], severe chronic obstructive pulmonary disease \[III-IV\], chronic kidney disease requiring hemodialysis)
- Patients with platelet count \< 100,000, INR \> 1.4, or an elevated PT or APTT (reversal of coumadin is permitted but the patient must not require coumadin during the acute hospitalization). Irreversible coagulopathy either due to medical condition or prior to randomization
- Pregnant (positive pregnancy test) or lactating females (likelihood of altered coagulation function associated with the high estrogen/progesterone state)
- Irreversibly impaired brainstem function (bilateral fixed, dilated pupils and extensor motor posturing), GCS less than or equal to 4
Key Trial Info
Start Date :
June 4 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 15 2028
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT07166146
Start Date
June 4 2025
End Date
March 15 2028
Last Update
September 10 2025
Active Locations (1)
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1
The Department of Neurosurgery, China International Neuroscience Institute, Xuanwu Hospital, Capital Medical University,
Beijing, China