Status:

RECRUITING

Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment

Lead Sponsor:

Postgraduate Institute of Dental Sciences Rohtak

Conditions:

Asymptomatic Irreversible Pulpitis

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal ...

Detailed Description

The primary goal of endodontic therapy is to eradicate microbial infection within the root canal system and prevent reinfection. Thorough debridement and disinfection of the apical third are crucial, ...

Eligibility Criteria

Inclusion

  • 18-65 years of age of either sex
  • Asymptomatic teeth having pulpal necrosis with apical periodontitis in a mandibular molar (no response to EPT or cold test)
  • Radiographic evidence of periapical radiolucency corresponding to a periapical index (PAI) score \>/=3 in mesial root of mandibular molars

Exclusion

  • Patients who were medically compromised
  • Patients with initial apical binding file (IABF) size more than 20
  • Pregnancy; lactation \& contraceptives.
  • Positive history of antibiotic use within the past month or required antibiotic premedication for dental treatment (including infective endocarditis or pros thetic joint prophylaxis -

Key Trial Info

Start Date :

April 18 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 18 2027

Estimated Enrollment :

270 Patients enrolled

Trial Details

Trial ID

NCT07166679

Start Date

April 18 2025

End Date

April 18 2027

Last Update

September 10 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

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Pgids Rohtak

Rohtak, India