Status:
RECRUITING
The Impacts of Gluten-free Diet in Patients With Ankylosing Spondylitis
Lead Sponsor:
Saglik Bilimleri Universitesi
Conditions:
Ankylosing Spondylitis
Eligibility:
All Genders
18-64 years
Phase:
NA
Brief Summary
Subclinical intestinal inflammation and intestinal permeability have been reported in patients with ankylosing spondylitis. Gluten is one of the main triggers of zonulin releaseand gluten intake may c...
Detailed Description
Ankylosing Spondylitis (AS) is a chronic, progressive, inflammatory rheumatic disease that severely impairs patients' quality of life and functional capacity. The gut-joint axis theory in the pathogen...
Eligibility Criteria
Inclusion
- diagnosis of axial SpA defined by ASAS criteria
- Adults (aged 18-64 years)
- stable treatment (NSAID and/or DMARD) for at least 3 months
- provide written informed consent and submit to the requirements of the study
Exclusion
- Any diet at the time of inclusion or within 3 months prior to inclusion;
- have a history of celiac disease;
- have a history of Ulcerative Colitis, Crohn's Disease and Irritable Bowel Syndrom
- patients with Type 1 and Type 2 Diabetes Mellitus
- patients with Hashimoto Thyroiditis
- are pregnant, breastfeeding,
- patients who have used omega-3 and vitamins (A, C, E) regularly in the last 3 months.
- BMI \<18,50 kg/m2
- BMI ≥29,99 kg/m2
Key Trial Info
Start Date :
January 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT07166874
Start Date
January 31 2025
End Date
May 31 2026
Last Update
September 10 2025
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
Bakırköy Dr. Sadi Konuk Training and Research hospital
Istanbul, Turkey (Türkiye)
2
İstanbul Medeniyet University
Istanbul, Turkey (Türkiye)
3
İstanbul Sağlık Bilimleri University
Istanbul, Turkey (Türkiye)
4
Marmara University
Istanbul, Turkey (Türkiye)