Status:
RECRUITING
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
Lead Sponsor:
University of Kansas Medical Center
Conditions:
Pre-frail
Pre-Frail Older Adults
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body compositi...
Detailed Description
Frailty is characterized by weakness, muscle loss, and physical impairment. It is suggested that long term oxidative stress might contribute to frailty. Glutathione (GSH), an antioxidant in cells, is ...
Eligibility Criteria
Inclusion
- Pre-frail according to Fried's phenotype
- Age 65 to 85
- Speak English as primary language and able to read and write in English
- Stable medication for ≥ 30 days
- Not already taking whey protein over the past 30 days
Exclusion
- Acute or chronic kidney disease
- Recent major health concerns
- Insulin-requiring diabetes
- Cancer requiring chemotherapy or radiation within the past 5 years
- Cardiac event (i.e., MI, etc.) in the past year
- Dementia or neurodegenerative disease
- Clinical trial or investigational drug or therapy participation within 30 days of the screening visit or during enrollment in the current study
- MRI contraindications (pacemaker, aneurysm clips, artificial heart valves, metal fragments, foreign objects or claustrophobia)
- Dairy Allergy or excluding dairy from diet for other reasons
- Weight \> 350 lbs.
- The presence of major psychiatric disorders within the past 3 years including depression, anxiety, and alcohol (over 3 drinks/day or a total of 18 drinks/week) or drug abuse.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07167277
Start Date
October 1 2025
End Date
February 1 2026
Last Update
September 11 2025
Active Locations (1)
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1
The University of Kansas Medical Center
Kansas City, Kansas, United States, 66160