Status:

RECRUITING

EUS-guided FNB-induced PANCREatitis Assessment

Lead Sponsor:

University of Tehran

Conditions:

Pancreatitis, Acute

EUS Guided Biopsy

Eligibility:

All Genders

18+ years

Brief Summary

This is a descriptive analytical study to investigate the prevalence and risk factors for pancreatitis after Endoscopic Ultrasonography-guided Fine Needle Biopsy (EUS-FNB) in patients at Shariati Hosp...

Detailed Description

EUS-guided tissue acquisition is an advanced diagnostic procedure for evaluating and diagnosing pancreatic, ampullary, and biliary tract tumors due to its high accuracy and minimally invasive nature. ...

Eligibility Criteria

Inclusion

  • Inpatients and outpatients aged 18 years or older undergoing EUS-guided FNB from a solid or cystic lesion in one of the following locations:
  • Pancreas
  • Ampulla of Vater
  • Distal CBD, defined as the intrapancreatic portion of the CBD where the FNB needle passes through the pancreas during biopsy

Exclusion

  • Patients who undergo concurrent ERCP in the same day
  • Patients experiencing an ongoing episode of acute pancreatitis during EUS-FNB
  • Patients undergoing EUS-guided FNA
  • Uncorrectable coagulopathy (INR \> 1.5)
  • Uncorrectable thrombocytopenia (platelet \< 50,000)
  • Decline to participate in the study and sign the informed consent form
  • Patients undergoing EUS-guided FNB from the proximal CBD where the FNB needle does not traverse the pancreas

Key Trial Info

Start Date :

September 11 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 12 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT07168863

Start Date

September 11 2025

End Date

March 12 2027

Last Update

September 15 2025

Active Locations (1)

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1

Shariati Hospital, Digestive Diseases Research Institute

Tehran, Tehran Province, Iran, 1411713135