Status:

RECRUITING

Identifying Genetic Targets in Gynecological Tumors

Lead Sponsor:

Azienda USL Reggio Emilia - IRCCS

Conditions:

Ovarian Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

This observational study aims to identfy genetic targets involved in the pathogenesis of gynecological tumors, with a focus on high-grade serous ovarian carcinoma. Using a triple approach - in silico,...

Detailed Description

Ovarian cancer is the leading cause of death among gynecological malignanciens. High-grade serous ovarian carcinoma (HGSOC) represents the most common and aggressive subtype. Growing evidence suggests...

Eligibility Criteria

Inclusion

  • Adult women ≥18 years old
  • Histologically confirmed diagnosis of epithelial ovarian cancer (including high- grade serous, endometrioid, mucinous, clear cell, or mesonephric-like histotypes)
  • Signed informed consent (for prospective cases) or ethically approved waiver (for retrospective samples)

Exclusion

  • Refusal to sign informed consent
  • Diagnosis of low-grade or non-epithelial ovarian tumors
  • Patients whose clinical or pathological data are unavailable or insufficient for study inclusion

Key Trial Info

Start Date :

November 17 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2027

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT07169396

Start Date

November 17 2021

End Date

November 1 2027

Last Update

September 11 2025

Active Locations (1)

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Azienda USL IRCCS di Reggio Emilia

Reggio Emilia, Italy