Status:
ENROLLING_BY_INVITATION
Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)
Lead Sponsor:
Chulalongkorn University
Conditions:
Demodex Blepharitis
Meibomian Gland Dysfunction (MGD)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Primary Objective: To evaluate the efficacy of LLLT, IPL, and IPL + LLLT in re ducing demodex count in patients with Demodex Blepharitis. Secondary Objectives: To evaluate the efficacy of LLLT, IPL...
Eligibility Criteria
Inclusion
- All patients who received a definite diagnosis of demodex blepharitis based on cylindrical dandruff at the base of the lashes and the presence of at least one alive demodex mites on eyelid margin by microscopy
- Age \>18 years.
- Patients who can understand and follow the study instructions and can adhere to the scheduled follow-up plan.
Exclusion
- Patients who received previous treatment IPL or LLLT
- Poor compliance with eyelid scrubbing using tea tree oil (TTO)
- Dead demodex mite on lash.
- Contraindication of IPL: Skin Fitzpatrick scale V/VI, patients with pigmented lesions on the treatment area (Eyelid, Cheek).
- Pregnancy or breastfeeding.
- Active Skin disease: facial skin cancer, graft-versus-host disease, systemic lupus erythaematosus
- Active eye infection: recurrent herpes simplex
- Other lid disease ocular trauma, ocular deformity scar, exophthalmos, eyelid insufficiency
- Patients with pigmented lesion on area of treatment.
Key Trial Info
Start Date :
January 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT07169461
Start Date
January 16 2025
End Date
December 30 2025
Last Update
September 11 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chulalongkorn University
Pathum Wan, Bangkok, Thailand, 10330