Status:

NOT_YET_RECRUITING

Hyperbaric Oxygen Treatment for Necrotizing Fasciitis and Necrotizing Soft Tissue Infections

Lead Sponsor:

Corewell Health West

Conditions:

Necrotizing Fascitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to learn if hyperbaric oxygen is beneficial in treating necrotizing infections and decreasing rates of morbidity and mortality. This study therefore has two aims: 1...

Detailed Description

Necrotizing fasciitis and necrotizing soft tissue infections are a complicated group of infections dominated largely by polymicrobial infections that rapidly spread through the skin and soft tissues. ...

Eligibility Criteria

Inclusion

  • Age: 18 years old
  • Patients with documented necrotizing fasciitis or necrotizing soft tissue infection as assessed during initial bedside evaluation, in conjunction with available laboratory values, imaging showing gas in soft tissues consitent with necrotizing infection, or surgical debridement of necrosis of fascia, muscle, and variable levels of soft tissue involvement
  • Patient or advocate is able to sign consent

Exclusion

  • Pediatric patients
  • Pregnant patients
  • Patients deemed unlikely to survive or unable to go to surgical debridement

Key Trial Info

Start Date :

November 14 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 14 2027

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT07170020

Start Date

November 14 2025

End Date

November 14 2027

Last Update

September 12 2025

Active Locations (1)

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1

Corewell Health

Grand Rapids, Michigan, United States, 49503