Status:
NOT_YET_RECRUITING
MULTIVALVE : A Prospective Multicentre Study of Multiple and Mixed Valvular Heart Disease
Lead Sponsor:
French Cardiology Society
Conditions:
Valvular Heart Disease
Eligibility:
All Genders
18+ years
Brief Summary
Multiple and mixed valvular heart disease (MMVD) is a common condition in clinical practice. It corresponds to a combination of stenotic or leaky lesions on two or more heart valves (multiple valve di...
Detailed Description
National, Prospective, Multicentric Registry. Patients with a diagnosis of MMVD identified by echocardiography will be included and followed up at 1, 2, 3 and 5 years.
Eligibility Criteria
Inclusion
- Age ≥18 years
- The patient has been informed of the study and has not refused to participate.
- An echocardiographic diagnosis of MMVD is defined as having at least two moderate to severe valvulopathies, as assessed by a cardiologist using transthoracic echocardiography (TTE), on one or more valves. This is in line with the recommendations of the ESC, the ASE, and expert opinion.
Exclusion
- History of valve surgery or percutaneous valve intervention involving the valve in question.
- A history of infective endocarditis, whether treated surgically or not, confirmed according to the modified Duke criteria.
- Acute infective endocarditis at the time of evaluation for inclusion, confirmed according to the modified Duke criteria.
- Complex congenital heart disease.
- Patients who are already included in the European EACVI-MMVD study.
- Pregnant women
- Patients not affiliated to social security
- Patients who are minors
- Patients under guardianship, curatorship or judicial supervision
- Patients who refuse to participate in this register.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2032
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT07176507
Start Date
October 1 2025
End Date
October 1 2032
Last Update
September 16 2025
Active Locations (2)
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1
Chu Lille- Hopital Cardiologique
Lille, France
2
Chu Lariboisiere (Aphp)
Paris, France