Status:
NOT_YET_RECRUITING
LiverTREM-1: Hepatic TREM-1 Expression and Prognosis in Severe Alcoholic Hepatitis
Lead Sponsor:
Central Hospital, Nancy, France
Conditions:
Severe Alcoholic Hepatitis
Eligibility:
All Genders
18+ years
Brief Summary
Background \& Rationale Severe alcohol-related hepatitis (SAH) is a serious condition with a 3-month mortality rate of \~30%. Diagnosis and prognosis are complex due to non-specific and insensitive cl...
Detailed Description
Study Title Official Title: Liver TREM-1: Hepatic Expression of TREM-1 in Severe Alcoholic Hepatitis Brief Summary (250 words max) Severe alcohol-associated hepatitis (sAH) is a life-threatening li...
Eligibility Criteria
Inclusion
- Cases:
- Individuals who received full information about the study and did not object to the use of their data within this research.
- Patients managed in one of the intensive care or hepatogastroenterology departments at CHRU de Nancy for severe alcohol-related hepatitis between January 1, 2013, and December 31, 2023.
- Archived liver biopsy slides available at CHRU de Nancy.
- Adult patients at the time of diagnosis.
- Controls:
- Individuals who received full information about the study and did not object to the use of their data within this research.
- Patients treated and operated on at CHRU de Nancy for hepatocellular carcinoma, colorectal cancer liver metastasis, or cholangiocarcinoma between January 1, 2013, and December 31, 2023.
- Archived liver biopsy slides available at CHRU de Nancy.
- Adult patients at the time of diagnosis.
Exclusion
- • None
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT07176741
Start Date
October 1 2025
End Date
December 1 2026
Last Update
September 16 2025
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