Status:
RECRUITING
Prospective Cohort Study on the Relationship Between Exosomal Peroxiredoxin 1 (PRDX1) and Postoperative Liver Metastasis
Lead Sponsor:
Mu-qing Yang
Conditions:
Colorectal Cancer
Liver Metastases From Colorectal Cancer
Eligibility:
All Genders
19-80 years
Brief Summary
The occurrence of liver metastasis after curative surgery for resectable colorectal cancer is an important cause of death for patients. Accurately identifying high-risk patients for metastasis and int...
Eligibility Criteria
Inclusion
- Age between 19-80 years old, gender not limited;
- Can comply with the requirements of the research visit plan and other protocols;
- Voluntarily participate and sign an informed consent form; ④ Diagnosed with colon adenocarcinoma through pathological examination; ⑤ Patients who have completed colorectal radical surgery.
Exclusion
- Patients who cannot complete radical surgery for colorectal cancer;
- Patients with liver diseases (chronic hepatitis B, hepatitis C, severe fatty liver, cirrhosis);
- Patients who require combined organ resection;
- Combine patients with other malignant tumors or blood or immune system diseases; ⑤ Prior to tumor resection, any anti-tumor treatment, including radiotherapy, chemotherapy, and molecular targeted therapy, has been performed; ⑥ After surgery, it was found that the mesenteric vein branch of the specimen could not obtain blood due to severe infiltration or other reasons.
- Patients with severe postoperative complications leading to delayed treatment (Clavien-Dindo grade III or above).
Key Trial Info
Start Date :
February 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2026
Estimated Enrollment :
260 Patients enrolled
Trial Details
Trial ID
NCT07177742
Start Date
February 15 2021
End Date
November 30 2026
Last Update
September 22 2025
Active Locations (1)
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1
Shanghai Tongji Hospital, Hepatobilliary Surgery Center, Tongji University
Shanghai, Shanghai Municipality, China, 200065