Status:
COMPLETED
Investigation of the Relationship Between Peripheral and Central Metabolic Changes Caused by Fasting
Lead Sponsor:
Nils Opel
Collaborating Sponsors:
University Hospital, Bonn
Johann Wolfgang Goethe University Hospital
Conditions:
Healthy
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Fasting has become an increasingly popular intervention for improving both physical and mental health. This study aims to explore the biological mechanisms underlying the positive effects of low calor...
Detailed Description
Therapeutic fasting, specifically Buchinger fasting, is a widely recognized method in integrative medicine. It is frequently used to treat a variety of chronic diseases, including inflammatory and met...
Eligibility Criteria
Inclusion
- Normal weight at study inclusion (BMI 18.5-25)
- Generally good physical condition without serious previous illnesses
- For female participants, only participants taking hormonal contraception are included
Exclusion
- MRI contraindication: cardiac pacemakers, hearing aids, neurostimulation, insulin pumps, other potentially ferromagnetic implants, screws, clips, prostheses, metal splinters, etc., pregnancy, claustrophobia, extensive tattoos, medication that impairs thermoregulation
- Comorbidity: neurological or psychiatric conditions, cognitive impairments, chronic somatic disorders
- Intake of more than 40g of pure alcohol (for men) or more than 20g of pure alcohol (for women), smoking, regular drug use
- Pregnancy or nursing
- Current or within the past five years eating disorder, vegan diet or fasting within the past six months
- Regular medication intake
Key Trial Info
Start Date :
October 4 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 28 2024
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT07178106
Start Date
October 4 2024
End Date
November 28 2024
Last Update
September 17 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Psychiatry and Psychotherapy, University Hospital Jena
Jena, Thuringia, Germany, 07743