Status:
RECRUITING
A Study of SCAD Using Stress Contrast Echocardiography
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Spontaneous Coronary Artery Dissection
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contra...
Eligibility Criteria
Inclusion
- Adult \>18 years old
- Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history
Exclusion
- Unable to give consent
- Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.
- Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.
- Pregnant.
- Unable to interrupt breastfeeding.
- Within 3 months of a heart attack.
- Severe aortic stenosis.
- Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).
Key Trial Info
Start Date :
November 25 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07178509
Start Date
November 25 2025
End Date
September 1 2027
Last Update
January 7 2026
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905