Status:
COMPLETED
A Precision Medicine Approach to the Prevention of Depression in Patients With Atrial Fibrillation
Lead Sponsor:
University of Southern Denmark
Collaborating Sponsors:
Aalborg University Hospital
Esbjerg Hospital - University Hospital of Southern Denmark
Conditions:
Atrial Fibrillation (AF)
Depression - Major Depressive Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the proposed project is to test a new therapist-assisted, eHealth intervention (HOPE-AF) targeted to prevent depression in patients with atrial fibrillation (AF). AF is the most common ...
Detailed Description
HOPE-AF represents a novel and pioneering approach to improving the HRQoL and prognosis of patients with AF through the prevention of depression, a seminal and debilitating risk factor for the onset o...
Eligibility Criteria
Inclusion
- Age ≥18 years
- Diagnosis of paroxysmal or persistent AF \[if persistent AF, duration \< 2 years\]
- Able to use and access a computer or tablet/iPad to adhere to the intervention - Proficient in the Danish language (reading and writing)
- Ability to provide informed written consent.
Exclusion
- Depression \[Hospital Anxiety and Depression Scale: HADS-D ≥11 (moderate symptoms)
- Anxiety \[Hospital Anxiety and Depression Scale: HADS-A ≥11 (moderate symptoms)
- Severe psychiatric or neurological disorder (e.g., schizophrenia or dementia)
- In need of psychiatric help due to comprehensive psychiatric issues, diagnosed or not
- Seeing a psychologist or mental health professional for the treatment of depression and anxiety
- Experiencing significant life stressors that hinder adherence to the HOPE-AF treatment
- Participating in another research project involving intervention for depression
- Not being able or willing to spend 1-2 hours on the intervention each week
Key Trial Info
Start Date :
April 19 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 17 2025
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT07178691
Start Date
April 19 2024
End Date
March 17 2025
Last Update
September 17 2025
Active Locations (3)
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1
Aalborg University Hospital
Aalborg, Denmark, 9100
2
University Hospital Esbjerg and Grindsted, University of Southern Denmark
Esbjerg, Denmark, 6700
3
Zealand University Hospital, Roskilde, Department of Cardiology
Roskilde, Denmark, 4000