Status:
NOT_YET_RECRUITING
DDAVP Effect by TEG6 in Cardiac Surgery
Lead Sponsor:
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions:
Intraoperative Bleeding
Eligibility:
All Genders
18+ years
Brief Summary
Cardiopulmonary bypass (CPB) is a process that uses a pump that temporarily takes over the function of the heart and lungs during cardiac surgery to maintain blood circulation and oxygenation. Using C...
Detailed Description
Cardiopulmonary bypass (CPB) during cardiac surgery is frequently complicated by disturbances in coagulation parameters and platelet function. Desmopressin (DDAVP) has been utilized to enhance platele...
Eligibility Criteria
Inclusion
- Age 18 years and above
- Undergoing elective cardiac surgery with cardiopulmonary bypass
- Able to provide informed consent
Exclusion
- Hyponatremia
- Allergy to desmopressin or its components
- History of coronary artery disease with thrombosis
- Recent history of thromboembolic events (Stroke/TIA/DVTs)
- Severe Renal Impairment Creatinine Clearance\<30 ml/min
- Inability to communicate in the English language
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07179991
Start Date
October 1 2025
End Date
December 31 2027
Last Update
September 18 2025
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