Status:
COMPLETED
Propranolol for Pediatric Migraine: A Prospective Clinical Study
Lead Sponsor:
Kayseri University
Conditions:
Pediatric Migraine
Headache Disorders
Eligibility:
All Genders
6-16 years
Phase:
NA
Brief Summary
This prospective, controlled clinical trial was conducted to evaluate the effectiveness of propranolol compared with structured behavioral therapy in pediatric patients diagnosed with primary migraine...
Detailed Description
Migraine is among the most common neurological disorders in children and adolescents, often leading to significant disability, reduced school performance, and impaired quality of life. Although propra...
Eligibility Criteria
Inclusion
- Diagnosis of primary migraine (with or without aura) according to ICHD-3 criteria
- Age between 6 and 16 years
- Minimum of 4 migraine attacks per month
- No history of prophylactic migraine therapy within the last 3 months
- Written informed consent obtained from parents or legal guardians
Exclusion
- Secondary headaches due to underlying pathologies (e.g., tumors, infections, vascular malformations)
- Chronic systemic or psychiatric disorders (e.g., epilepsy, major depression)
- Contraindications to propranolol (e.g., asthma, cardiac conduction defects)
- Incomplete clinical data or loss to follow-up
Key Trial Info
Start Date :
January 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2023
Estimated Enrollment :
178 Patients enrolled
Trial Details
Trial ID
NCT07180043
Start Date
January 1 2021
End Date
December 30 2023
Last Update
September 18 2025
Active Locations (1)
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1
Kayseri University
Kayseri, Kayseri, Turkey (Türkiye), 38130