Status:

COMPLETED

Microbiota and Probiotic Therapy in Ulcerative Colitis Patients

Lead Sponsor:

Tanta University

Conditions:

Microbiota

Probiotic Therapy

Eligibility:

All Genders

18+ years

Brief Summary

This study aimed to evaluate the role of microbiota and probiotics in Egyptian patients with ulcerative colitis.

Detailed Description

Inflammatory bowel disease (IBD) is a group of chronic diseases that significantly affects patients' quality of life and is mainly represented by Crohn's disease (CD) and ulcerative colitis (UC). The...

Eligibility Criteria

Inclusion

  • Patients more than 18 years.
  • Patients with ulcerative colitis in remission as assessed by the clinical activity index (CAI) ≤ 4, endoscopic index (EI) ≤ 4, and no signs of acute inflammation on histological examination.

Exclusion

  • Active ulcerative colitis.
  • Cardiac, hepatic, or renal disease.
  • Pregnancy.
  • History of major colonic surgery.
  • Patients with any malignancy.
  • Previously taking other probiotics.
  • Use of steroids within the last 4 weeks before study entry.
  • Use of antibiotics within the last 2 weeks before study entry

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2024

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT07180186

Start Date

January 1 2022

End Date

May 1 2024

Last Update

September 18 2025

Active Locations (1)

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Tanta University

Tanta, El-Gharbia, Egypt, 31527