Status:

RECRUITING

Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension

Lead Sponsor:

University General Hospital of Patras

Conditions:

Magnesium Sulfate

Remifentanil

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection durin...

Detailed Description

Functional endoscopic sinus surgery (FESS) is commonly performed under controlled hypotension in order to minimize intraoperative bleeding and optimize the surgical field. However, controlled hypotens...

Eligibility Criteria

Inclusion

  • Inclusion Criteria :
  • Adult patients (≥18 years old). Scheduled for F.E.S.S (Functional endoscopic sinus surgery ) under general anesthesia.
  • Able to provide informed consent
  • Exclusion Criteria:
  • Emergency surgery. ASA physical status IV-V. Severe hepatic or renal dysfunction. Known allergy or contraindication to study drugs. Pregnant or lactating women. unable to provide informed consent
  • Patients unwilling or unable to provide consent.

Exclusion

    Key Trial Info

    Start Date :

    September 11 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    March 20 2026

    Estimated Enrollment :

    150 Patients enrolled

    Trial Details

    Trial ID

    NCT07181564

    Start Date

    September 11 2025

    End Date

    March 20 2026

    Last Update

    September 18 2025

    Active Locations (1)

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    University General Hospital of Patras

    Pátrai, Achaia, Greece, 26504