Status:

NOT_YET_RECRUITING

Ketamine in Central Sensitization

Lead Sponsor:

University Hospitals Cleveland Medical Center

Conditions:

Endometriosis

Chronic Pelvic Pain

Eligibility:

FEMALE

18-89 years

Phase:

PHASE4

Brief Summary

The purpose of this research study is to see if ketamine infusion during surgery can decrease pain after surgery. Ketamine is a medication commonly used as part of anesthesia during surgery and is app...

Eligibility Criteria

Inclusion

  • age range 18-89
  • ASA classification I-III
  • outpatient elective laparoscopy for endometriosis

Exclusion

  • known allergy or contraindication to ketamine
  • History of substance use disorder, including alcohol or marijuana use, both current and remote
  • History of severe psychiatric illness, including schizoaffective disorder, bipolar disorder, psychosis, or decompensated psychiatric condition , excluding anxiety and depression
  • Current Intraoperative complications

Key Trial Info

Start Date :

February 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2028

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT07182032

Start Date

February 1 2026

End Date

June 30 2028

Last Update

November 26 2025

Active Locations (1)

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1

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States, 44106