Status:
NOT_YET_RECRUITING
Blood Flow and Oxygenation in the Portal Vein in Subjects With Chronic Narrowing of the Blood Vessels to the Gut
Lead Sponsor:
Rigshospitalet, Denmark
Conditions:
Chronic Mesenteric Ischemia
Eligibility:
All Genders
18+ years
Brief Summary
In this study the investigators will, with an Magnetic Resonance Imaging (MRI) method, measure the oxygen content in the portal vein, which conduct the blood from the guts to the liver. Examinations w...
Detailed Description
Chronic mesenteric ischemia is a rare but potentially life threatening disease, in which atherosklerotic narrowing of the blood supply to the guts causes meal related abdominal pain, and subsequent we...
Eligibility Criteria
Inclusion
- \- Written informed consent
- Male or female persons \> 18 years
- Subjects with postprandial abdominal pain considered compatible with mesenteric ischemia, and severe stenosis of the SMA and eventually other mesenteric arteries, diagnosed with CT-angiography or Doppler ultrasound
- OR subjects with severe stenosis of the SMA and eventually other mesenteric arteries, diagnosed with CT-angiography or Doppler ultrasound, but not postprandial pain
Exclusion
- \- Serious concurrent illness
- BMI \> 30
- Cardiac arrhythmia
- Anemia with Hgb \< 7,0 mmol/l
- Pregnancy or breastfeeding (urine HCG is performed on all fertile women)
- Systolic blood pressure \< 90 or \> 200 mmHg
- Claustrophobia
- Patients who, in the judgement of the investigator, is incapable of participating
- Metallic foreign objects in the body, or pacemakers
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2028
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07182669
Start Date
October 1 2025
End Date
October 1 2028
Last Update
September 19 2025
Active Locations (1)
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1
Dept. of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet
Copenhagen, State, Denmark, 2100 Ø