Status:
RECRUITING
Novel Skin Barrier Product Versus Petrolatum for Skin Barrier Dysfunction
Lead Sponsor:
Makati Medical Center
Conditions:
Psoriasis
Atopic Dermatitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if a novel barrier topical product works to treat barrier dysfunction in adults. It will also learn about the safety of the novel barrier topical product. T...
Detailed Description
The goal of this randomized controlled trial is to determine the efficacy of a new barrier product (containing ceramide, virgin coconut oil, cholesterol) versus petrolatum in adults with skin barrier ...
Eligibility Criteria
Inclusion
- Clinical diagnosis of mild skin barrier dysfunction, including:
- Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators.
- Mild to moderate chronic plaque psoriasis, defined as total body surface area (BSA) involved: ≤3% to 10%.
- Contact dermatitis
- Seasonal xerosis or clinically evident skin dryness
- Symmetrical or bilateral test areas available (volar forearm)
- Willing and able to provide informed consent and adhere to study procedures
Exclusion
- Failure to meet any of the above inclusion criteria
- Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatment
- Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within 2 weeks
- Open wounds or evidence of secondary infection at test sites
- Pregnant or breastfeeding women
- Multiple nevi, tattoos, dense body hair in the test areas
- Debilitated or immunocompromised subjects
- Known or suspected hypersensitivity to the interventional product (or its ingredients) or petrolatum
- Refusal or failure to comply with the schedule of visits at the test site.
Key Trial Info
Start Date :
August 31 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT07183423
Start Date
August 31 2025
End Date
October 1 2025
Last Update
September 19 2025
Active Locations (1)
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1
VMV Skin Research Center & Clinics
Makati City, National Capital Region, Philippines, 1229