Status:
RECRUITING
Metabolic Effects of Short-Chain Fatty Acids in Healthy Individuals
Lead Sponsor:
University of Copenhagen
Conditions:
Healhty
Other: Short-Chain Fatty Acid (SCFA)
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The primary objective of this study is to investigate the acute physiological and metabolic effects of ingesting the short-chain fatty acids (SCFA)s propionate (three carbon atoms long; C3:0) and buty...
Detailed Description
The study will be conducted as a block-randomized cross-over study in healty participants (n=10). The participants will undergo two experimental days of three hours separated by a two to four weeks wa...
Eligibility Criteria
Inclusion
- Male or female.
- Age between 18-40 years old
- BMI between 18.5-29
Exclusion
- Diabetes
- Kidney- or liver disease
- Pregnant, lactating or planning to become pregnant within the study period
- Supplementation with SCFAs
- Supplementation with B12 vitamin
- Special dietary habits (e.g. vegan/ketogenic diet)
- Ongoing cancer treatment
- Metabolic or absorptive disorders, gastric bypass operation, or use of medication affecting metabolism or food absorption
- Crohn's disease, ulcerative colitis or short bowel syndrome
- Inability, physically or mentally, to comply with the procedure required by the study protocol as evaluated by the primary investigator, study manager or clinical responsible
Key Trial Info
Start Date :
September 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2030
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT07183488
Start Date
September 10 2025
End Date
September 1 2030
Last Update
November 17 2025
Active Locations (1)
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1
University of Copenhagen
Copenhagen, Copenhagen N, Denmark, 2200