Status:
NOT_YET_RECRUITING
Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial
Lead Sponsor:
University Hospital, Angers
Conditions:
Intensive Care (ICU)
Central Venous Catheter Related Infections
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In the intensive care unit, patients' care and secure drugs administration require a central venous catheter. These invasive devices can lead to complications, particularly infections. Most preventive...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Adult patient
- Any ICU patient with a central venous catheter (inserted by venipuncture) in place for less than 72 hours and with an expected dwell time of at least 7 days
- Patient affiliated with or covered by a social security system
- Patient who has given verbal consent or written consent from a third party or in the event that the patient is unable to give consent.
- Exclusion Criteria
- Patient with a documented bloodstream infection at the time of inclusion
- Patient whose central venous catheter has been in place for more than 72 hours
- Patient with suspected catheter-related infection
- Patient whose study catheter was inserted using a guidewire exchange
- Patient previously enrolled in the study during the same ICU stay
- Patient whose condition, according to the clinician, does not allow safe placement of a central venous catheter, such as:
- Allergy to catheter material
- Confirmed deep vein thrombosis at the time of insertion
- Inflammatory skin disorder at the insertion site
- Patient admitted for extensive burns
- Inadequate understanding of the French language
- Pregnant, breastfeeding, or postpartum woman
- Person deprived of liberty by judicial or administrative decision
- Person receiving involuntary psychiatric care
- Person under legal guardianship or other legal protection measure
Exclusion
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2028
Estimated Enrollment :
2830 Patients enrolled
Trial Details
Trial ID
NCT07183592
Start Date
January 1 2026
End Date
April 1 2028
Last Update
September 29 2025
Active Locations (20)
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1
La Réunion University Hospital
Saint-Pierre, La Réunion, France, BP350 97448
2
Albi Hospital
Albi, France, 81000
3
Angers University Hospital
Angers, France, 49933
4
Belfort Hospital
Belfort, France, 90015