Status:
RECRUITING
Comparison of Heparin Anti-Xa Activity From Central Venous Catheter Samples Using a 5 mL Syringe Flush or a Vacuum Tube Flush Versus Peripheral Vein Samples in ICU Patients
Lead Sponsor:
Centre Hospitalier Régional d'Orléans
Conditions:
Anticoagulants and Bleeding Disorders
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal is to investigate whether blood samples drawn from a central venous catheter can provide reliable measurements of unfractionated heparin (UFH) anti-Xa activity, compared to the standard metho...
Detailed Description
Unfractionated heparin (UFH) is widely used in intensive care units (ICUs) and requires close monitoring, most commonly through the measurement of anti-Xa activity. The reference method for anti-Xa m...
Eligibility Criteria
Inclusion
- Person (or support person/relative if unable to do so) who has agreed to participate in the study
- 18 years of age or older
- Hospitalized in intensive care medicine
- Having a central venous catheter with at least three lumens (internal jugular, subclavian or femoral) already in place
- Receiving continuous intravenous unfractionned heparin, with target Anti-Xa activity between 0.3 and 0.7 IU/ml.
Exclusion
- Protected person (under guardianship or curatorship)
- Person under court protection
- Person deprived of liberty
- Person not affiliated to the French social security
- Pregnant or breast-feeding woman
Key Trial Info
Start Date :
September 22 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07183605
Start Date
September 22 2025
End Date
October 1 2026
Last Update
November 25 2025
Active Locations (1)
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1
Chu Orleans
Orléans, France, 45067